14 Nov 1519Cortés seizes Moctezuma,making him a puppet ruler
1519–1533Enriquillo leads Taínorevolt on Hispaniola
19 Apr–29 May 1520Cortés defeatsCuban expeditionsent to arrest him
Apr–Dec 1520Smallpox kills millionsin Aztec Empire
22 May 1520Spanish massacreAztecs in Great Templeof Tenochtitlan